Solution – Mad Cow Disease
This clue could mislead you into thinking the solution was a word hidden in the clue – "discovered in" would be a hint that way. But the setter has trickily made it an anagram of "meadow – cases I'd" – this is indicated by the word "treated". And of course Mad Cow Diseases is a "beastly ailment" in the sense that it is an animal disease and is also awful.
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